【摘 要】
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Objective To study the effect of electroacupuncture (EA) on epidermal growth factor( EGF),calcitonin gene-related peptide(CGRP) and gastric mucosa in stress rat
【机 构】
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Tangdu Hospital, Fourth Military Medical University,Xi’an 710038， China
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Objective To study the effect of electroacupuncture (EA) on epidermal growth factor( EGF),calcitonin gene-related peptide(CGRP) and gastric mucosa in stress rats. Methods 72 SD rats were randomized into 3 groups:control group,stress group and EA group.Each group were divided into 3 small groups by 1,3,5 d test time.By radioactive-immunon-assay and Guth methods, ;the changes of EGF.CGRP in plasma and ulcer index (UI) were analyzed. Results Stress group compared with control group, the level of EGF decreased (P< 0.05);but UI increased (P< 0.01).In the EA group compared with stress group, plasma EGF increased (P< 0.05);but UI decreased (P< 0.01).The changes of CGRP in test 5d was more obvious than in 1d in EA group (P< 0.01).Conclusion EA can protect gastric mucosa in stress rats, EGF, CGRP take part in this function.CGRP in EA group can be effected by test time.
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