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目的:探讨美托洛尔治疗充血性心力衰竭(CHF)的临床疗效。方法:将58例CHF患者随机分为美托洛尔治疗组和对照组,对照组患者服用血管紧张素转换酶抑制剂(ACEI)、利尿剂和强心甙,美托洛尔治疗组患者在对照组用药的基础上加用小剂量美托洛尔,3个月后进行比较。结果:美托洛尔治疗组患者的心功能、心率、左室射血分数(LVEF)、左室舒张末内径(LVEDD),与对照组相比,均有显著差异性(P<0.05)。结论:CHF患者在服用利尿剂、ACEI和强心甙治疗的基础上加用美托洛尔可取得更好的疗效。
Objective: To investigate the clinical efficacy of metoprolol in the treatment of congestive heart failure (CHF). Methods: Fifty-eight CHF patients were randomly divided into metoprolol treatment group and control group. Patients in the control group were given angiotensin converting enzyme inhibitor (ACEI), diuretic and cardiac glycosides, metoprolol treatment group Control group based on the use of small doses of metoprolol, 3 months after the comparison. Results: The cardiac function, heart rate, left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter (LVEDD) in metoprolol group were significantly higher than those in control group (P <0.05). CONCLUSION: Metoprolol can be used to treat CHF patients on the basis of taking diuretics, ACEI and cardiac glycosides.