产后溶血性尿毒症综合征是指产后以急性微血管病性溶血性贫血、血小板减少及急性肾衰竭三大特征为主的综合征。本病发病急、进展快。其病因与妊娠期凝血功能异常、分娩中使用缩宫素及麦角生物碱,并与遗传、免疫及感染等因素有关。其发病机制是肾脏局部的微血管病性溶血及血管内凝血。目前尚无特效治疗方法,早期采用血浆置换、腹膜透析,以及大剂量皮质激素应用等综合治疗,改善患者预后。 Postpartum hemolytic uremic syndrome refers to postpartum with acute microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure characterized by the three major syndromes. The incidence of acute disease, rapid progress. The etiology and coagulation disorders during pregnancy, use of oxytocin and ergot alkaloid during childbirth, and genetic, immune and infection and other factors. The pathogenesis of renal microvascular hemolysis and intravascular coagulation. There is no effective treatment, the early use of plasma exchange, peritoneal dialysis, and high-dose corticosteroid and other comprehensive treatment to improve patient outcomes.