论文部分内容阅读
报告1例免疫表型为CD4-,CD8+,CD56+的蕈样肉芽肿(MF)。患者男,21岁。双侧腋窝、躯干及腹股沟大片状灰红色至棕红色斑8年,呈渐进性发展,无任何自觉症状。腹部皮损组织病理示表皮轻度角化不全,真皮内致密淋巴细胞,部分细胞入侵表皮。免疫组化示CD4-,CD8+,CD3+,CD43+,CD68灶状+,CD30灶状+,CD56+,TIA-1-,EBV-。诊断:蕈样肉芽肿。给予阿维A胶囊30mg/d,顿服,糠酸莫米松乳膏及多磺酸粘多糖乳膏外用。皮损缓解,临床随访4个月,病情稳定。
A case of mycosis-like granuloma (MF) with CD4-, CD8+, and CD56+ immunophenotype was reported. Male patient, 21 years old. Bilateral axillary, trunk, and groin have large patches of gray-red to brown-red patches for 8 years with progressive development without any symptoms. The histopathology of abdominal lesions showed that the epidermis had mild parakeratosis, dense lymphocytes in the dermis, and some cells invaded the epidermis. Immunohistochemistry showed CD4-, CD8+, CD3+, CD43+, CD68 +, CD30 +, CD56+, TIA-1-, and EBV-. Diagnosis: Mycosis granuloma. Avi-A capsules were given at a dose of 30 mg/d, Dayton clothing, mometasone furoate cream and polysulphonic acid mucopolysaccharide cream for topical use. The skin lesions were relieved and clinically followed up for 4 months. The condition was stable.