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肿瘤组织样本取自 1 978～ 1 990年期间按照英国哥伦比亚指导原则治疗的 1 96 0 0多例Ⅰ～Ⅲ期乳腺癌患者 ,对其中 930例参加了随机或Ⅱ期研究的患者建立了组织芯片法 (tissuemicro array)。观察终点为从乳腺癌相关死亡事件计算的乳腺癌 2 0年生存率(BrCaSS) ,检测了下述多种肿
Tumor samples were taken from 1 96 0 patients with stage I-III breast cancer who were treated according to British Columbia guidelines between 1978 and 1990. Tissue microarrays were constructed in 930 patients who participated in the randomized or phase II study Tissue micro array. The end point was the 20-year breast cancer survival rate (BrCaSS) calculated from breast cancer-related deaths and the following multi-swollen