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晚近有不少材料提示,部分少年期发病的糖尿病是由于自身免疫所致。但是,由于未能从患者血清中测得直接与胰岛起作用的自身抗体,所以糖尿病的自身免疫学说未能确立。本文报导用间接免疫萤光技术从下列4组病人中检查抗胰岛细胞抗体,检查对象分(1)甲组:20例伴有慢性肾上腺皮质功能减退症的少年期发病并依赖胰岛素的糖尿病患者,所有病例都含有抗肾上腺抗体,其中9例还伴有其他自身免疫性疾病,并有相应的抗体;(2)乙组:20例少年期发病并依赖胰岛素的糖尿
Recently, many materials suggest that some of the juvenile onset of diabetes due to autoimmunity. However, the autoimmune theory of diabetes has not been established because of the failure to detect autoantibodies that directly affect islets from patient sera. This article reports the use of indirect immunofluorescence technique to examine anti-islet cell antibodies from the following 4 groups of patients: (1) Group A: 20 adolescents with chronic adrenocortical hypofunction and insulin-dependent diabetes mellitus, All cases contain anti-adrenal antibodies, of which 9 cases are associated with other autoimmune diseases, and the corresponding antibodies; (2) Group B: 20 cases of juvenile onset and dependent on insulin in diabetes