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目的:探讨卡前列素防治高危产妇剖宫产术中及术后出血的临床效果。方法:将80例可能存在宫缩乏力高危因素的产妇分为两组,对照组应用宫缩素予以止血,观察组于对照组治疗基础之上应用卡前列素氨丁三醇进行治疗。比较两组出血量及不良反应发生率。结果:观察组术中及术后出血量均显著低于对照组,差异显著(P<0.05);比较两组用药后不良反应发生率,对照组为17.5%,观察组为15.0%,比较不具有统计学意义(P>0.05)。结论:卡前列素防治高危产妇剖宫产术中及术后出血的临床效果肯定,值得临床推广应用。
Objective: To investigate the clinical effect of carboprost in the prevention and treatment of high risk maternal cesarean section and postoperative bleeding. Methods: Eighty pregnant women with possible risk factors for uterine atony were divided into two groups. The control group was treated with orpanoid to stop the bleeding. The observation group was treated with carboprost tromethamine on the basis of the control group. The amount of bleeding and the incidence of adverse reactions in both groups were compared. Results: The intraoperative and postoperative bleeding in the observation group were significantly lower than those in the control group (P <0.05). The incidence of adverse reactions was 17.5% in the control group and 15.0% in the observation group compared with the control group Statistically significant (P> 0.05). Conclusion: The clinical effect of cardoprost in preventing and treating high-risk maternal cesarean section and postoperative bleeding is certain and worthy of clinical application.