论文部分内容阅读
在初步筛选操作中发现某些类固醇类存在时,微生物对硫酸新霉素呈现更大的敏感性,用革兰氏阳性及革兰氏阴性细菌,仅对小球菌属及链球菌属,有显著的增强,此篇研究中应用金黄色葡萄球菌及溶血性链球菌进行实验。在体试验中含有2.0mg/ml皮质素或皮质素半琥珀酸钠,氧化皮质素及Δ′氧化皮质素中,约需要菌株小于10—50倍的新霉素即可抑制此二种细菌。类固醇类的醋酸盐在增加抗菌力方面无效。一组实验结果1meg/ml的新霉素B对黄金色葡萄球菌有制菌作
In the initial screening operation found that the presence of certain steroids, the microorganisms showed greater sensitivity to neomycin sulfate, with Gram-positive and Gram-negative bacteria, only for the genus and genus Streptococcus, significant Enhancement, this study the application of Staphylococcus aureus and hemolytic streptococcus experiments. In vivo tests containing 2.0 mg / ml cortisol or corticosteroid sodium succinate, cortisol and Δ ’cortisol, about the need for strains less than 10-50 times the new neomycin can inhibit these two kinds of bacteria. Steroid acetates are ineffective at increasing antibacterial activity. A group of neomycin B test results 1meg / ml of Staphylococcus aureus bacteria