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目的观察奥美拉唑联合去甲肾上腺素治疗上消化道出血疗效。方法 84例上消化道出血患者,随机分为治疗组与对照组,各42例。均给予制酸、扩容、保护胃黏膜等治疗,治疗组在此基础上再给予去甲肾上腺素口服,观察两组疗效及不良反应。结果治疗组总有效率明显高于对照组(P<0.05),治疗前后两组肝肾功能、血常规、尿常规无明显异常。结论奥美拉唑联合去甲肾上腺素治疗上消化道出血疗效较显著,两者联用可明显提高上消化道出血的疗效,值得临床应用。
Objective To observe the curative effect of omeprazole combined with norepinephrine on upper gastrointestinal bleeding. Methods 84 patients with upper gastrointestinal bleeding were randomly divided into treatment group and control group, 42 cases in each group. Both were given acid, expansion, protection of gastric mucosa and other treatment, the treatment group on this basis and then given norepinephrine orally, the two groups were observed efficacy and adverse reactions. Results The total effective rate in the treatment group was significantly higher than that in the control group (P <0.05). There was no significant difference in liver and kidney function, blood routine and urine before and after treatment in both groups. Conclusion Omeprazole combined with norepinephrine treatment of upper gastrointestinal bleeding more significant effect, the combination of the two can significantly improve the efficacy of upper gastrointestinal bleeding, is worthy of clinical application.