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家兔及啮齿动物是最常应用的实验动物.由于科学实验上的需要,常对这些动物应用麻醉药以缓介外科手术中的疼痛.众所周知,各种因素都可影响麻醉药的作用,除本文重点论述的药物因素外,还与动物种属,个体差异以及饲养管理条件有关.例如,多数穴居动物,特别是家兔、因长期笼养,很少运动,其肺部不发达(平均重为14克),对空气中CO_2的耐受性很低(较一般农畜敏感一倍),对空气中O_2利用率极低,而呼出的CO_2却高于其它动物.穴居动物呼吸系统的另一特征,是呼吸时
Rabbits and rodents are the most commonly used experimental animals, and due to scientific and experimental needs, these animals are often given narcotics to ease the pain during surgery. It is known that various factors can affect the action of anesthetics, For example, most burrowing animals, especially rabbits, have little exercise due to long-term cage-rearing and their lungs are underdeveloped (average weight 14 g), low tolerance to CO 2 in the air (twice as sensitive as that of livestock and poultry), very low utilization of O 2 in the air and higher CO 2 exhaled than other animals. A feature is when breathing