将海藻酸钠/明胶共混液滴入含有CaCl2的壳聚糖醋酸溶液中,制备出SA/CS/GT三元复合水凝胶微球。改变SA/GT的质量配比、盐离子浓度、温度,考察不同条件下对复合微球溶胀度的影响。结果表明:当SA∶GT质量比为10∶0.6、10∶0.8,CaCl2浓度为3%~4%,所成微球的溶胀性能较好;随温度的升高,溶胀度不断增大。 SA / CS / GT ternary composite hydrogel microspheres were prepared by dropping sodium alginate / gelatin blend solution into chitosan acetate solution containing CaCl2. The effects of SA / GT ratio, salt ion concentration and temperature on the swelling degree of composite microspheres under different conditions were investigated. The results show that when the mass ratio of SA: GT is 10: 0.6, 10: 0.8, CaCl2 concentration is 3% ~ 4%, the swelling properties of the microspheres are better. With the increase of temperature, the swelling degree increases.