【摘 要】
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Multispecies coalescent (MSC) is the extension of the single-population coalescent model to multiple species.It integrates the phylogenetic process of species divergences and the population genetic process of coalescent,and provides a powerful framework f
【机 构】
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Department of Genetics,Evolution and Environment,University College London,London WC1E 6BT,UK;Depart
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Multispecies coalescent (MSC) is the extension of the single-population coalescent model to multiple species.It integrates the phylogenetic process of species divergences and the population genetic process of coalescent,and provides a powerful framework for a number of inference problems using genomic sequence data from multiple species,including estimation of species divergence times and population sizes,estimation of species trees accommodating discordant gene trees,inference ofcross-species gene flow and species delimitation.In this review,we introduce the major features of the MSC model,discuss full-likelihood and heuristic methods of species tree estimation and summarize recent methodological advances in inference of cross-species gene flow.We discuss the statistical and computational challenges in the field and research directions where breakthroughs may be likely in the next fewyears.
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