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目的探究冠心病患者白蛋白尿与血清尿酸水平的关系。方法选取冠心病患者68例,于患者入院第2天24 h内采集尿液进行检测,以患者尿液中白蛋白含量为划分标准,将患者分为阳性观察组(白蛋白含量≥30 mg/24 h)和阴性对照组(白蛋白含量<30 mg/24 h),各34例,分别检测并对比两组的血清尿酸(UA)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C),和低密度脂蛋白胆固醇(LDL-C)水平,并研究分析冠心病患者产生白蛋白尿的主要危险因素。结果阳性观察组患者UA、TG和LDL-C水平均高于阴性对照组,HDL-C水平低于阴性对照组,差异有统计学意义(P<0.05);经过Logistic回归分析发现,UA是引发冠心病患者产生白蛋白尿的主要危险因素。结论白蛋白尿呈阳性的冠心病患者UA水平显著高于阴性患者,UA水平与患者白蛋白尿具有明显相关性,是导致患者产生白蛋白尿的重要因素。
Objective To investigate the relationship between albuminuria and serum uric acid in patients with coronary heart disease. Methods Sixty-eight patients with coronary heart disease (CAD) were enrolled in this study. Urine was collected within 24 hours of admission on the second day of admission. Urinary albumin was divided into positive observation group (albumin content≥30 mg / 24 h) and negative control group (albumin content <30 mg / 24 h), 34 cases in each group. Serum uric acid (UA), triglyceride (TG), high density lipoprotein cholesterol -C), and low-density lipoprotein cholesterol (LDL-C) levels, and study the main risk factors for albuminuria in patients with coronary heart disease. Results The levels of UA, TG and LDL-C in the positive observation group were significantly higher than those in the negative control group, while the HDL-C levels were lower than the negative control group (P <0.05). Logistic regression analysis showed that UA was the trigger The main risk factors for albuminuria in patients with coronary heart disease. Conclusions UA levels in patients with positive albuminuria are significantly higher than those in patients with negative UA. There is a significant correlation between UA and albuminuria in patients with albuminuria, which is an important factor in patients with albuminuria.