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肿瘤细胞对化疗药物耐药常导致化疗的失败,因此寻求较为有效的耐药预测指标势在必行,这对于临床患者用药的选择、化疗有效性的提高及耐药逆转的研究具有重要意义。吉西他滨(Gemcitabine,2-2-difluoro-2’-deoxycytidine,dFdC)是临床较为常用的化疗药物,对肺癌、乳腺癌、胰腺癌?
Therefore, it is imperative to seek a more effective drug resistance prediction index, which is of great significance for the choice of clinical medication, the improvement of the efficacy of chemotherapy and the reversal of drug resistance. Gemcitabine (2-2-difluoro-2’-deoxycytidine, dFdC) is a more commonly used clinical chemotherapy drugs for lung cancer, breast cancer, pancreatic cancer?