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目的研究胆管中段癌的临床诊断和治疗方法及其对患者预后的影响。方法 24例胆管中段癌患者作为研究对象,回顾性分析患者的临床基本资料和诊断治疗的方法以及效果。结果 24例患者中,治疗后并发症发生率29.2%(7/24),实施根治性切除手术的15例患者,术后5例出现手术并发症,并发症的发生率33.3%,包括腹腔脓肿1例,胆瘘2例,胰瘘2例。其余患者中,出现切口延期愈合1例,胃肠功能障碍1例。所有并发症经治疗均痊愈,其中腹腔脓肿和胆瘘、胰瘘通过穿刺引流治疗。手术治疗中无一例死亡的情况。经随访,行根治性切除手术的患者1年生存率80.0%(12/15),3年生存率53.3%(8/15)。结论胆管中段癌具有病理类型单一、根治性切除率高的特点。对患者及时有效的诊断和治疗对于患者的预后具有重要的意义。
Objective To study the clinical diagnosis and treatment of middle bile duct carcinoma and its influence on the prognosis of patients. Methods Twenty-four patients with central bile duct cancer were studied retrospectively. The clinical data and diagnosis and treatment methods were analyzed retrospectively. Results Among the 24 patients, the incidence of postoperative complications was 29.2% (7/24). Fifteen patients undergoing radical resection and postoperative complications occurred in 5 patients. The incidence of complications was 33.3%, including abdominal abscess 1 case, 2 cases of biliary fistula, 2 cases of pancreatic fistula. The remaining patients, delayed wound healing occurred in 1 case, gastrointestinal dysfunction in 1 case. All complications were cured by treatment, including abdominal abscess and biliary fistula, pancreatic fistula drainage by puncture. Surgical treatment without any deaths. At follow-up, the 1-year survival rate was 80.0% (12/15) and the 3-year survival rate was 53.3% (8/15) in patients undergoing radical resection. Conclusion The middle bile duct carcinoma has the characteristics of single pathological type and high radical resection rate. The timely and effective diagnosis and treatment of patients is of great significance to the prognosis of patients.