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介绍P2 7蛋白的分子生物学特点、对细胞周期的调控和在肿瘤中的研究进展。P2 7蛋白是一种新发现的周期素依赖激酶抑制剂 ,属于细胞周期的负性调控因子。P2 7基因及其产物的异常表达可能与某些肿瘤的发生、发展有着密切的关系
The molecular biology of P27 protein, the regulation of cell cycle and the research progress in tumors are introduced. P27 protein is a newly discovered cyclin-dependent kinase inhibitor that is a negative regulator of the cell cycle. The abnormal expression of P27 gene and its products may be closely related to the occurrence and development of certain tumors.