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多囊卵巢综合征(polycystic ovary syndrome,PCOS)是以高雄激素血症为主要特征的内分泌代谢紊乱性疾病,是生殖内分泌领域研究的热点和难点课题之一。近年来大量研究显示,PCOS患者普遍处于一种慢性低度炎症状态,并且这种炎症环境与高雄激素血症的发展密切相关,或者高雄激素血症诱导炎症产生,亦或炎症刺激卵巢产生高雄激素血症,两者相互影响,共同促进PCOS的发生、发展。
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder characterized by hyperandrogenism and is one of the hot and difficult topics in the field of reproductive and endocrine research. In recent years, a large number of studies have shown that PCOS patients are generally in a state of chronic low-grade inflammation, and the inflammatory environment is closely related to the development of hyperandrogenism, or hyperandrogenemia induced inflammation, or inflammation stimulates ovarian hyperandrogenism Serum, the two affect each other and jointly promote the occurrence and development of PCOS.