GSTP1基因是一重要的DNA损伤修复基因,属抑癌基因,抑癌基因GSTP1CpG岛高度甲基化可能参与了肝癌的发生发展,可能作为一个很好的分子生物标志物,对慢性肝病进行动态监测、肝癌的早期筛查、诊断和预测预后均具有重要的临床意义。1GSTP1基因的结构Cowell等[1]从Cosmid文库中分离了 GSTP1 gene is an important gene repair DNA damage, is a tumor suppressor gene, tumor suppressor gene GSTP1CpG island hypermethylation may be involved in the development of liver cancer, may be used as a good molecular biomarkers of chronic liver disease dynamic monitoring , Early screening of liver cancer, diagnosis and prognosis have important clinical significance. Structure of 1GSTP1 Gene Cowell et al [1] isolated from the Cosmid library