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随着科学技术和制药工业的迅速发展,抗菌药物品种不断增多,作用机理越来越复杂,为了发挥抗菌药物在临床上的治疗作用,提高治愈率,必须提倡合理应用抗菌药。1抗菌药物的合理应用定义世界卫生组织(WHO)将抗菌药的合理应用定义为:“抗菌药的应用需符合成本-效益原则,以最大限度地发挥其临床治疗作用,并将药物相关的不良反应和细菌耐药性的发生降低到最低限度。”美国卫生保
With the rapid development of science and technology and pharmaceutical industry, the variety of antibacterial drugs is increasing and the mechanism of action is more and more complicated. In order to exert the clinical therapeutic effect and improve the cure rate of antibacterial drugs, it is necessary to promote rational use of antibacterials. 1 Rational application of antimicrobials Definition The rational use of antimicrobials by the World Health Organization (WHO) is defined as: “The use of antimicrobial agents should be cost-effective in order to maximize its clinical therapeutic role and to be drug related Adverse reactions and bacterial resistance to occur to a minimum. ”Health Care in the United States