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解偶联蛋白-2(UCP-2),是解偶联蛋白家族的新成员,它的结构与解偶联蛋白-1相似,但它广泛分布在机体的各种组织中,尤以白色脂肪含量最高,因此它在肥胖的发生过程中应有重要作用。目前关于解偶联蛋白-2的生理作用和生化特点还不十分清楚。本文主要就这种蛋白的结构、活性、组织分布及其调节作用等几个方面做一综述。
Uncoupling protein-2 (UCP-2), a new member of the uncoupling protein family, has a similar structure to uncoupling protein-1 but is widely distributed in various tissues of the body, especially white fat The highest content, so it should play an important role in the occurrence of obesity. Currently on the uncoupling protein -2 physiological and biochemical characteristics are not yet clear. This article mainly reviews the structure, activity, tissue distribution and regulation of this protein.