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目的分析我院2011至2015年临床分离的鲍曼不动杆菌在临床标本中的分布特点及其常用抗菌药物的耐药性。方法常规方法分离582株菌株,测定最低抑菌浓度(MIC),根据美国临床标准化委员会(CLSI)2012标准评价抗菌药物敏感性,用WHONET5.6软件和SPSS19.0软件进行统计分析。结果临床分离的鲍曼不动杆菌主要来源于痰液(83.68%);以神经外科病房检出率最高(38.32%);该菌对复方磺胺甲噁唑和亚胺培南耐药率较低,分别为49.66%和55.15%;对其余多种抗菌药物耐药率在62.37%以上;其中分离出多重耐药鲍曼不动杆菌348株(59.79%)。结论鲍曼不动杆菌的耐药率较高且具有多重耐药性。
Objective To analyze the distribution characteristics of clinically isolated Acinetobacter baumannii in our hospital from 2011 to 2015 and the antibiotic resistance of commonly used antibiotics. Methods 582 isolates were isolated by conventional methods. The MICs were determined. The antimicrobial susceptibility was evaluated according to the CLSI (2012) standard. The data were analyzed by WHONET5.6 software and SPSS19.0 software. Results Acinetobacter baumannii was mainly derived from sputum (83.68%). The neurosurgical ward had the highest detection rate (38.32%). The rate of resistance to sulfamethoxazole and imipenem was lower , Which were 49.66% and 55.15% respectively. The resistance rates of other antibacterials were over 62.37%. 348 (59.79%) were isolated from Acinetobacter baumannii. Conclusion Acinetobacter baumannii has higher drug resistance rate and multiple drug resistance.