沙利度胺又称反应停,具有抗炎、免疫调节、抗肿瘤的作用,临床应用广泛,近年来国内有文献报道其不良反应,现概括如下:1诱发药疹吴超等报道,患女,31岁,因慢性唇炎给予沙利度胺50mg口服,2/日,3天前患者胸、背部及双手足曾出现散在红色斑、丘疹,伴明显瘙痒,口服本品后皮疹面积渐扩大,躯干及四肢泛发大量红色斑、丘疹,表面覆少量鳞屑,遂停药,予对症治疗,4周后皮疹基本消退~([1])。 Thalidomide, also known as the reaction to stop, with anti-inflammatory, immunomodulatory, anti-tumor effect, a wide range of clinical applications, the domestic literature reported in recent years, the adverse reactions are summarized as follows: 1 induced drug rash Wu Chao et al reported that women, 31 years old, due to chronic cheilitis given thalidomide 50mg orally, 2 / day, 3 days before the patient chest, back and hands feet had appeared scattered red spots, pimples, with significant itching, after oral administration of this product rash area gradually expanded, A large number of red spots and pimples were found on the trunk and extremities. The skin was covered with a small amount of scales, and the drug was stopped for symptomatic treatment. The rash subsided after 4 weeks (1).