论文部分内容阅读
目的探讨脑脊液置换配合鞘内给药治疗结核性脑膜炎的临床效果。方法选择30例结核性脑膜炎患者,随机分为观察组和对照组各15例,对照组采用常规抗结核药物治疗,观察组在此基础上加用脑脊液置换配合鞘内给药,比较两组疗效。结果观察组治愈率为73.3%(11/15),好转率为20%(3/15),总有效率为93.3%(14/15);对照组治愈率为46.7%(7/15),好转率为26.7%(4/15),总有效率为73.3%(11/15),两组比较差异有统计学意义(P<0.05),观察组疗效要优于对照组。结论脑脊液置换配合鞘内给药治疗结核性脑膜炎效果确切,值得在临床使用。
Objective To investigate the clinical effect of cerebrospinal fluid replacement combined with intrathecal administration in the treatment of tuberculous meningitis. Methods Thirty patients with tuberculous meningitis were randomly divided into observation group (15 cases) and control group (15 cases). The control group was treated with conventional anti-TB drugs. The observation group was treated with cerebrospinal fluid replacement combined with intrathecal administration. Efficacy. Results The cure rate in the observation group was 73.3% (11/15), the improvement rate was 20% (3/15) and the total effective rate was 93.3% (14/15). The cure rate in the control group was 46.7% (7/15) The improvement rate was 26.7% (4/15), and the total effective rate was 73.3% (11/15). The difference between the two groups was statistically significant (P <0.05). The observation group had better effect than the control group. Conclusion Cerebrospinal fluid replacement with intrathecal administration of tuberculous meningitis is effective and worthy of clinical application.