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肠道缺血-再灌注是多器官衰竭(MOF)的一种重要的致病机理。创伤后MOF最初表现为成人呼吸窘迫综合征(ARDS),通常认为中性粒细胞在ARDS的发生中起增加毛细血管通透性的重要介导作用。肝衰竭通常紧随其后,表现为血清胆红素隐匿性升高。血清白蛋白渗出量的增加可提示毛细血管通透性增高,同时晚近建立的酮体比率(KBR)测定(即血中乙酰乙酸与β-羟丁酸的比值)可灵敏地反映肝功能的
Intestinal ischemia-reperfusion is an important pathogenic mechanism of multiple organ failure (MOF). MOF initially manifests as adult respiratory distress syndrome (ARDS) after trauma, and neutrophils are generally considered to play an important mediating role in increasing capillary permeability in the development of ARDS. Usually followed by liver failure, manifested as an occult elevation of serum bilirubin. An increase in serum albumin excretion may indicate an increase in capillary permeability, while a newly established ketone body ratio (KBR) assay (ie, the ratio of acetoacetate to beta-hydroxybutyrate in the blood) can sensitively reflect liver function