目的:了解无锡市慢性阻塞性肺疾病(简称慢阻肺)患病现状,分析其相关危险因素。方法:二阶段随机抽样法确定10个调查点,样本总量、各年龄层的设定参照中国慢阻肺患病率调查方法的研究设定,被调查者完成慢阻肺筛查问卷,总分大于9分的对象根据中华医学会呼吸病学分会慢阻肺诊治指南的诊断标准进行确诊,确诊患者参照呼吸困难量表(m MRC)进行呼吸困难程度评估,并调查最近1年内发生急性加重的次数,根据2013 GOLD指南的标准分为A、B、C、D 4组,并结合肺功能FEV1占预计值的百分比进行分级。结果:共发放慢阻肺筛查问卷2 500份,回收资料完整的共2 491份,其中筛查诊断慢阻肺201例,占调查人数的8.0%,其中A组87例(43.3%),B组25例(12.3%),C组53例(26.4%),D组36例(18.0%)。70岁及以上组与70岁以下各组的慢阻肺患病率比较差异有统计学意义;多因素Logistic回归分析结果显示,高年龄、吸烟指数大于200支·年~(-1)、家族呼吸疾病史和生物燃料暴露史是发生慢阻肺的独立危险因素。结论:高年龄、吸烟、家族呼吸疾病史和生物燃料暴露史是慢阻肺的致病高危因素,早诊早干预,以降低其危害性。 Objective: To understand the prevalence of chronic obstructive pulmonary disease (COPD) in Wuxi and to analyze its related risk factors. Methods: Two-stage random sampling method was used to determine 10 survey sites. The total sample size and the age-specific settings were set according to the research settings of the Chinese COPD prevalence survey. The respondents completed the chronic obstructive pulmonary disease screening questionnaire, Subjects with a score greater than 9 were diagnosed according to the diagnostic criteria of the Chronic Obstructive Pulmonary Disease Diagnosis and Treatment Guide of the Respiratory Disease Branch of the Chinese Medical Association. The diagnosed patients were assessed for degree of dyspnea with reference to the Respiratory Distress Scale (m-MRC), and the acute exacerbations The patients were divided into groups A, B, C, and D 4 according to the standards of the 2013 GOLD guidelines, and graded according to the percentage of predicted pulmonary function FEV1. RESULTS: A total of 2 500 COPD questionnaires were sent out, and 2 491 samples were retrieved completely. Among them, 201 cases of chronic obstructive pulmonary disease were screened and diagnosed, accounting for 8.0% of the total, of which 87 cases (43.3%) in group A, , 25 cases (12.3%) in group B, 53 cases (26.4%) in group C, and 36 cases (18.0%) in group D. The prevalence of chronic obstructive pulmonary disease (COPD) in 70-year-old group and above-aged group was significantly different from that in the group of 70-year-old group. Multivariate Logistic regression analysis showed that the age, smoking index was more than 200 · years -1, Respiratory disease history and biofuel exposure history are independent risk factors for COPD. CONCLUSIONS: High age, smoking history, family history of respiratory disease and biofuel exposure history are the risk factors of COPD. Early diagnosis and early intervention can reduce its harmfulness.