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目的了解鲍曼不动杆菌临床分离菌株的耐药现状与耐药谱特征。方法收集分离的70株鲍曼不动杆菌,用K-B纸片法检测抗菌药物的耐药性。结果 70株鲍曼不动杆菌中,40株(57.14%)为多重耐药菌,6株(8.57%)为泛耐药菌株。鲍曼不动杆菌对亚胺培南、阿米卡星的耐药率最低,分别为30.00%和32.86%;其次是美罗培南、头胞吡肟,耐药率分别为38.57%,41.43%;对其余抗菌药的耐药率大多超过50.00%。结论本院鲍曼不动杆菌临床分离菌株多重耐药情况严重。
Objective To understand the drug resistance and clinical characteristics of Acinetobacter baumannii isolates. Methods Seventy strains of Acinetobacter baumannii were collected and tested for antibiotic resistance by K-B discography. Results Among the 70 Acinetobacter baumannii isolates, 40 (57.14%) were multi-drug resistant and 6 (8.57%) were pan-drug resistant. Acinetobacter baumannii had the lowest resistance rates to imipenem and amikacin, which were 30.00% and 32.86%, followed by meropenem and ceftazidime. The resistance rates were 38.57% and 41.43%, respectively. The rate of resistance to the remaining antibacterials was mostly over 50.00%. Conclusion The clinical isolates of Acinetobacter baumannii in our hospital have a serious multi-drug resistance.