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目的：观察高频双向喷射通气（ＨＦＴＪＶ）和常规机械通气（ＣＭＶ）对蒸气吸入性损伤犬的呼吸循环动力学参数、肺容量及血气的影响。方法：通过蒸气吸入致伤，复制了犬重度蒸气吸入性损伤模型。结果：①两种通气方式下呼吸系统总阻力（Ｒｒｓ）、肺阻力（ＲＬ）均显著高于对照值（Ｐ均＜０．０１），呼吸系统总顺应性（Ｃｒｓ）、肺顺应性（ＣＬ）均显著低于对照值（Ｐ均＜０．０５），但两者之间比较，Ｒｒｓ、ＲＬ和Ｃｒｓ、ＣＬ的变化均无显著性差异（Ｐ均＞０．０５）。②ＣＭＶ能引起ＣＯ２潴留；ＨＦＴＪＶ比ＣＭＶ显著增加ＣＯ２排出量（ＶＣＯ２，Ｐ＜０．０５），降低过高的ＰａＣＯ２（Ｐ＜０．０１）。③两种通气方式下功能残气量（ＦＲＣ）、心输出量（ＣＯ）、平均动脉压（ＭＡＰ）和ＰａＯ２均无显著变化（Ｐ均＞０．０５）。结论：两种通气方式均能克服气道阻力辅助呼吸，但不能使伤后高气道阻力和低肺顺应性恢复正常。ＣＭＶ的通气效率较低，可引起ＣＯ２潴留；ＨＦＴＪＶ的通气效率则明显优于ＣＭＶ，且能维持吸入性损伤犬的血气至正常水平。
Objective: To observe the effects of high frequency two-way jet ventilation (HFTJV) and conventional mechanical ventilation (CMV) on respiratory cycle kinetic parameters, lung volume and blood gas in dogs with vapor aspiration injury. Methods: Severe steam inhalation injury in dogs was replicated by steam inhalation injury. Results: ① The total respiratory resistance (Rrs) and lung resistance (RL) of the two ventilation modes were significantly higher than those of the control (P <0.01), total respiratory compliance (Crs) and lung compliance ) Were significantly lower than those of the control group (all P <0.05). However, there was no significant difference in Rrs, RL, Crs and CL between the two groups (P> 0.05). CMV can cause CO2 retention; HFTJV significantly increased CO2 emission (VCO2, P <0.05) and decreased PaCO2 (P <0.01) higher than CMV. ③ There was no significant change in functional residual mass (FRC), cardiac output (CO), mean arterial pressure (MAP) and PaO2 in both ventilation modes (P> 0.05). Conclusion: Both ventilation methods can overcome the airway resistance assisted breathing, but can not make the post-traumatic high airway resistance and low lung compliance back to normal. CMV ventilation efficiency is low, can cause CO2 retention; HFTJV ventilation efficiency was significantly better than CMV, and to maintain the inhalation injury dog’s blood gas to normal levels.