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我院从79年开始用液氮治疗恶性肿瘤,取得一定效果。最近采用喷射方法治疗球结膜或睑结膜表浅性肿瘤,疗效更为满意。本文对14例眼前部恶性肿瘤进行了治疗及临床观察,其中8例睑板腺癌,2例波文氏病,1例基底细胞癌,1例横纹肌肉瘤,1例鳞状上皮癌,1例肿物切除部分细胞癌变。3只眼为球结膜面,9只眼为脸结膜面,2只为眶内容挖出术后睑结膜面。其病变范围大小不等,大的可达1.5×1.0×1.0cm~3,小的仅裂隙灯下可见颗粒状改变。根据病情可分别选用:1.喷射法 1%地卡因麻醉后,用开睑器暴露肿瘤部位,然后用液氮器直接喷射局部直到形成白色冰晶,冻融3次,每次约15—20秒。复温后当时可见局部水肿充血、2—3天达反应高峰、约一周左右反应逐渐减轻消失,局部干燥结痂、至3—4周干痂脱落,病
Our hospital from 79 years of treatment of malignant tumors with liquid nitrogen, and achieved some results. The recent use of jet method for the treatment of conjunctival or conjunctival superficial tumors, the effect is more satisfactory. In this paper, 14 cases of anterior malignant tumors were treated and clinically observed, including 8 cases of meibomian gland carcinoma, 2 cases of Bowen’s disease, 1 case of basal cell carcinoma, 1 case of rhabdomyosarcoma, 1 case of squamous cell carcinoma, 1 case Mass resection of some cancerous cells. Three eyes were conjunctival surface, nine eyes were facial conjunctival surface, and two posterior conjunctival surface were excised for orbital contents. The range of lesion sizes, large up to 1.5 × 1.0 × 1.0cm ~ 3, only a small slit lamp visible granular changes. According to the disease can be used separately: 1. Spraying method 1% dexamethasone anesthesia, with open speckle exposing the tumor site, and then use liquid nitrogen directly spray local until the formation of white ice crystals, freeze-thaw 3 times, each about 15-20 second. After rewarming local edema was visible congestion, 2-3 days up to the peak, about a week or so gradually reduce the reaction disappeared, local dry scab, 3-4 weeks dry scab off, the disease