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目的探讨高血压对扩张型心肌病(DCM)心力衰竭(CHF)患者心室重构的影响。方法选择患有DCM临床体征符合NYHA分级Ⅲ～Ⅳ级且左室射血分数<40%的患者99例,其中伴高血压的患者30例为观察组,不伴有高血压的患者69例为对照组,比较2组临床资料及心脏彩超结果,并采用统计学方法比较2组间的差异。结果 2组临床资料比较无显著性差别;心脏彩超结果中室间隔厚度(IVSD)与左室后壁厚度(LVPWD)与对照组比较,差异有统计学意义(P<0.05)。结论高血压会引起扩张型心肌病心肌肥厚,加重心室重构。
Objective To investigate the effect of hypertension on ventricular remodeling in patients with dilated cardiomyopathy (DCM) and heart failure (CHF). Methods Ninety-nine patients with NYHA class Ⅲ ~ Ⅳ and LV ejection fraction <40% were enrolled in this study. Thirty patients with hypertension were selected as observation group and 69 patients without hypertension In the control group, the clinical data of two groups and the results of echocardiography were compared. The differences between the two groups were statistically analyzed. Results There was no significant difference in the clinical data between the two groups. The difference of IVSD and LVPWD between the two groups was statistically significant (P <0.05). Conclusion Hypertension can cause cardiac hypertrophy in dilated cardiomyopathy and aggravate ventricular remodeling.