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目的:探讨经导管封堵术治疗卵圆孔未闭(PFO)合并隐匿性卒中或短暂性缺血发作的近中期疗效。方法:随访2009-05至2015-12期间在阜外医院成功实施经导管PFO封堵术的PFO合并隐匿性卒中、短暂性缺血发作56例,并于术后24h、1个月、3个月、6个月复查经胸超声心动图、心电图、X线胸片,随后每隔6个月行电话随访。结果:56例患者中合并隐匿性卒中54例,合并短暂性缺血发作2例,53例(94.6%)使用北京华医圣杰公司PFO封堵器,术后应用阿司匹林6个月,平均随访(34.67±23.24)个月,所有患者术后均无卒中、短暂性缺血发作病史,术后均未见残余分流。结论:经导管PFO封堵术治疗PFO合并隐匿性卒中或短暂性脑缺血发作近中期疗效满意,仍需要进一步长期大规模随访。
Objective: To investigate the short-term and long-term efficacy of transcatheter closure of patent foramen ovale (PFO) complicated with occult or transient ischemic attack. Methods: Fifty-six patients with PFO with occlusive PFO and occult stroke and transient ischemic attack were successfully enrolled in Fu Wai Hospital from May 2009 to December 2015. The patients were followed up for 24 h, 1 month, 3 months Month, 6 months review of transthoracic echocardiography, electrocardiogram, X-ray, followed by telephone follow-up every 6 months. Results: Among the 56 patients, 54 cases were complicated with occult stroke, 2 cases had transient ischemic attack, and 53 cases (94.6%) were treated with Beijing Huayi Shengjie PFO occluder. Postoperative aspirin was used for 6 months. The average follow-up (34.67 ± 23.24) months. All patients had no history of stroke and transient ischemic attack after operation. No residual shunt occurred after operation. CONCLUSIONS: Catheterized PFO closure for the treatment of PFO with occult or transient ischemic attacks is satisfactory in the near to mid-term and further long-term large-scale follow-up is still needed.