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目的 :研究枳子水提取液对小鼠腹腔巨噬细胞释放一氧化氮的影响。方法 :NO以Griess试剂测定。结果 :浓度为 42～ 6 6 7μg生药 /ml的枳子水提取液能显著抑制小鼠腹腔巨噬细胞一氧化氮的释放。结论 :枳子水提取液对小鼠腹腔巨细胞释放一氧化氮的调节可能是其保肝作用机制之一。
Objective : To study the effect of water extract of gardenia on the release of nitric oxide from mouse peritoneal macrophages. Methods : NO was measured by Griess reagent. RESULTS : The water extract of Gardenia jasminoides with a concentration of 42-66.7μg crude drug/ml could significantly inhibit the release of nitric oxide from mouse peritoneal macrophages. Conclusion : The water extract of Gardenia jasminoides can regulate the release of nitric oxide from giant cells in the peritoneal cavity of mice, which may be one of the mechanisms of liver protection.