论文部分内容阅读
目的探讨本地区已婚妇女宫颈人乳头瘤病毒(HPV)感染的状况和基因分型。方法选择2013年1月至2014年12月因宫颈疾病或其他妇科疾病就诊已婚妇女150例,检测液基薄层细胞学检查(TCT)和HPV,并对HPV进行基因分型检测。结果辖区已婚妇女HPV感染率为25.33%,高危型-HPV(HR-HPV)占90.39%,以16、52、58、31和18等亚型为多见;将高度病变组的HPV总感染率、低危型-HPV(LR-HPV)和HR-HPV感染率与正常宫颈组比较,差异有统计学意义(P<0.05)。结论宫颈高度病变患者中HR-HPV感染率最高,应加强对已婚妇女行宫颈TCT筛查和HR-HPV基因分型的检测,更好地早期诊断、预测转归和指导临床治疗。
Objective To investigate the status and genotyping of cervical human papillomavirus (HPV) infection in married women in this area. Methods From January 2013 to December 2014, 150 married women were referred for cervical disease or other gynecological diseases. Serum-based TLCT and HPV were detected, and genotyping was performed on HPV. Results The HPV infection rate was 25.33% in married area and 90.39% in high-risk HPV (HPV-HPV), 16,52,58,31 and 18 subtypes were more common. In the highly pathological group, total HPV infection The rates of low-risk HPV-LRV HPV and HR-HPV infection were significantly different from those of normal cervix (P <0.05). Conclusion The highest HR-HPV infection rate is found in patients with cervical lesions. Cervical TCT screening and HR-HPV genotyping should be strengthened in married women, so that early diagnosis, prognosis and clinical treatment can be predicted.