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卵巢上皮新生物,通常称为囊肿,来源自卵巢表面上皮(卵腔上皮,间皮)的包涵物。这些包涵物被认为是由于表面上皮内陷而产生的。这样的内陷常见于近绝经期或刚过绝经期年龄的妇女的卵巢。卵巢表面由于“与老年患者垂体前叶卵泡刺激素分泌过剩相关”的局部基质增生而卷旋,曾被提出用以解释上皮的内陷。囊肿衍生的这一概念难以解释发生于较年青患者的囊肿的来源。事实上,良性囊肿最常见于20～50岁者,发病的高峰年龄为30～40多岁。已报告的恶性囊肿妇女的平均年龄约为51岁,约25％卵巢癌患者年龄小于50岁。所以,看来在生育期中的较早期即有小的,上皮囊肿生成包涵物之形成。
Epithelial ovarian neoplasms, commonly referred to as cysts, are derived from inclusions of the ovarian surface epithelium (ova epithelial, mesothelial). These inclusions are believed to be due to surface epithelial invagination. Such invagination is commonly found in the ovaries of women at or near the pre-menopausal age. Ovarian surfaces have been suggested to account for the invagination of the epithelium as they are coiled up due to local matrix hyperplasia associated with an excess of the anterior pituitary follicle-stimulating hormone secretion in elderly patients. The concept of cyst derivation can hardly explain the source of cysts that occur in younger patients. In fact, the most common benign cysts in 20 to 50 years of age, the peak incidence of 30 to 40 years of age. The reported average age of malignant cyst women is about 51 years and about 25% of ovarian cancer patients are younger than 50 years. Therefore, it appears that there is a small, epithelial cyst-forming inclusion formation earlier in the growth period.