新辅助治疗是在除外转移的情况下,在局部治疗前(手术或放疗)进行的全身药物治疗。乳腺癌的异质性决定了乳腺癌对药物治疗的敏感性存在较大的差异,用多基因表达谱模型来预测新辅助治疗疗效,为乳腺癌个体化治疗方案的选择提供了新的途径。文章简述预测性多基因表达谱在乳腺癌治疗中的应用。 Neoadjuvant therapy is systemic drug therapy prior to topical treatment (surgery or radiotherapy) with the exception of metastases. The heterogeneity of breast cancer determines that the sensitivity of breast cancer to drug treatment is quite different. Using the multi-gene expression profiling model to predict the effect of neoadjuvant therapy provides a new way for the individualized treatment options of breast cancer. The article briefly describes the application of predictive polygene expression in the treatment of breast cancer.