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患者女性,55岁,系躁郁症,病程反复发作约20年.1988年4月服用氯丙嗪50mg/d,白细胞为2.8～3.4×10~9/L,停药后白细胞恢复正常.同年10月27日因兴奋话多.好打扮1月余第三次住本科.体格检查无异常发现,实验室检查白细胞为5.6×10~9/L,中性0.82.10月31日～11月9日给予氯丙嗪250mg/d,11月9日白细胞为3.65×10~9/L,中性0.79.11月7日改用卡马西平0.4g/d,11月14日白细胞为4.45×10~9/L,中性0.82.治疗11天时体温39.6℃,咽充血,白细胞降至1.45×10~9/L,中性0.18,考虑为卡马西平所致白细胞
Female patients, 55 years old, Department of bipolar disorder, repeated episodes of about 20 years .In April 1988, taking chlorpromazine 50mg / d, leukocytes 2.8 ~ 3.4 × 10 ~ 9 / L, withdrawal leukocytes returned to normal. Oct. 27 because of the excitement and more. Good dress for the third time in January more than undergraduate. Physical examination showed no abnormalities, laboratory tests of white blood cells was 5.6 × 10 ~ 9 / L, neutral 0. 82. October 31 ~ November Chlorpromazine on the 9th 250mg / d, November 9 white blood cells 3.65 × 10 ~ 9 / L, neutral 0.79 November 7 to switch to carbamazepine 0.4g / d, November 14 leukocyte 4.45 × 10 ~ 9 / L, neutral 0.82. At 11 days of treatment, body temperature 39.6 ℃, pharyngeal congestion, leukopenia 1.45 × 10 ~ 9 / L, neutral 0.18, considered as carbamazepine-induced leukocytes