对 10例实体瘤患者采集自体骨髓 ,2 8小时内完成预处理 ,采髓后 70小时内回输。观察患者的血象变化和毒副反应。结果 :患者的骨髓均受严重抑制 ,但都获得造血重建 ,使患者的缓解期和生存期明显延长 ,生活质量改善 ;主要毒副反应是胃肠道反应。认为 CEC方案是一个毒性小、耐受性好、疗效高的预处理方案 For 10 patients with solid tumors, autologous bone marrow was collected and pretreatment was completed within 28 hours. The bone marrow was returned within 70 hours after pith harvesting. Observe the patient’s blood changes and toxicities. Results: The patients’ bone marrow were severely inhibited, but hematopoietic reconstitution was achieved. The remission and survival period of patients were significantly prolonged and their quality of life was improved. The main toxic and side effects were gastrointestinal reactions. It is considered that the CEC scheme is a pretreatment scheme with low toxicity, good tolerance, and high efficacy.