论文部分内容阅读
[目的]观察清肠解毒汤直肠滴入联合左氧氟沙星治疗急性细菌性痢疾疗效。[方法]使用随机平行对照方法,将100例住院患者按病志号抽签方法简单随机分两组;肠道隔离,补液、支持及对症治疗,忌生冷、油腻、辛辣、不洁饮食。对照组50例左氧氟沙星0.4g+生理盐水250mL,静滴,1次/d。治疗组50例清肠解毒汤(白头翁15g,黄连、黄芩、黄柏、大黄各10g,赤芍15g,木香、槟榔、佛手各10g),1剂/d,水煎150mL装瓶,液温36~40℃,患者排便后,取左侧卧位,肛管插入深度15~20cm,30min内直肠滴入,每晚1次;左氧氟沙星治疗同对照组。连续治疗8d为1疗程。观测临床症状、住院时间、住院费用、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈45例,有效5例,无效0例,总有效率100%;对照组痊愈30例,有效12例,无效8例,总有效率84.00%;治疗组疗效优于对照组(P<0.05)。症状及体征消失时间治疗组均少于对照组(P<0.05)。住院时间及住院费用治疗组均少于对照组(P<0.05)。[结论]清肠解毒汤直肠滴入联合左氧氟沙星治疗急性细菌性痢疾,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the effect of Qingchang Jiedu Decoction instillation in combination with levofloxacin for the treatment of acute bacillary dysentery. [Methods] Using randomized parallel control method, 100 inpatients were randomly divided into two groups according to the method of lot drawing of the disease; intestinal isolation, rehydration, support and symptomatic treatment, avoid cold, greasy, spicy, unclean diet. Control group, 50 cases of levofloxacin 0.4g + saline 250mL, intravenous infusion, 1 time / d. The treatment group, 50 cases of Qingchang Jiedu Decoction (Pulsatilla 15g, berberine, Scutellaria, Phellodendron, rhubarb each 10g, red peony 15g, woody, areca, bergamot 10g), 1 / d, decoction 150mL bottles, liquid temperature 36 ~ 40 ℃, the patient was defecate, take the left lateral position, the depth of anal insertion 15 ~ 20cm, 30min rectal infusion, nightly 1; levofloxacin treatment with the control group. Continuous treatment of 8d for a course of treatment. Observation of clinical symptoms, length of stay, hospitalization costs, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] 45 cases were cured, 5 cases were effective, 0 cases were ineffective and the total effective rate was 100%. In the control group, 30 cases were cured, 12 cases were effective, 8 cases were ineffective and the total effective rate was 84.00%. The treatment group was better than the control group (P <0.05). Symptoms and signs disappeared in the treatment group were less than the control group (P <0.05). Hospitalization and hospitalization costs were less in the treatment group than in the control group (P <0.05). [Conclusion] Qingchang Jiedu Decoction combined with levofloxacin in the treatment of acute bacillary dysentery by rectal infusion has satisfactory curative effect and no serious adverse reactions and is worth popularizing.