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探讨隐睾儿童血清雌激素与隐睾、附睾畸形三者之间的关系。我们对64例隐睾儿童手术前采血,用放射免疫分析法测定血清雌二醇(E2)值,与68例健康男孩对照比较(t检验)。术中观察睾丸和附睾之间的附着形态。结果:①隐睾儿童血清E2值(143.90±124.15pmol/L)明显高于正常对照组(45.48±39.13pmol/L),P<0.01;②隐睾合并附睾和(或)输精管畸形者占39.1%,且隐睾合并附睾畸形组与不合并附睾畸形组比较,血清E2值明显增高;③高位和腹股沟管型隐睾分别与皮下环型比较,血清E2明显增高,因此,隐睾胚胎期Woffian管的分化发育与血清E2水平之间存在某种内在性联系,可能是隐睾的重要发病因素。
To investigate the relationship between serum estrogen and cryptorchidism and epididymis deformity in children with cryptorchidism. Sixty-four children with cryptorchidism were sacrificed before operation, and serum estradiol (E2) was measured by radioimmunoassay, which was compared with 68 healthy boys (t test). Intraoperative observation of attachment between the testis and epididymis. Results: ① The serum E2 level in cryptorchidism group was significantly higher than that in the control group (45.98 ± 39.13pmol / L, P <0.01) (Or) vasectomy accounted for 39.1%, and cryptorchidism with epididymis deformity group and non-combined epididymal deformity group, serum E2 value was significantly higher; ③ high position and inguinal canal cryptorchidism compared with the subcutaneous ring, serum E2 Significantly increased, therefore, cryptorchid testis Woffian tube differentiation and serum E2 levels there is some intrinsic link may be an important risk factor for cryptorchidism.