Synthesis, radiolabeling and biological evaluation of butene amine oxime containing nitrotriazole as

来源 :Nuclear Science and Techniques | 被引量 : 0次 | 上传用户：baby_xiaojuan

【摘要】

：

99mTc-BnAO, as a nonnitroaromatic hypoxia marker, is the subject of intensive research in recent years. In this study, a butene amine oxime–nitrotriazole（Bn AO

【作者】

：

Qiang Zhang Tai-Wei Chu

【机构】

：

BeijingNationalLaboratoryforMolecularSciences

【出处】

：

Nuclear Science and Techniques

【发表日期】

：

2016年2期

【关键词】

：

细胞缺氧肿瘤模型生物学评价标记合成胺肟丁烯 S180 99mTc Butene amine oxime HypoxiaNitrotriazo

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99mTc-BnAO, as a nonnitroaromatic hypoxia marker, is the subject of intensive research in recent years. In this study, a butene amine oxime–nitrotriazole（Bn AO–NT）was synthesized and radiolabeled with 99mTc in high yield.Cellular uptakes of99mTc-Bn AO–NT

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Synthesis, radiolabeling and biological evaluation of butene amine oxime containing nitrotriazole as

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