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目的探讨儿童过敏性紫癜内镜下病变,以及与临床的关系,为早期诊断提供依据。方法2000年8月至2004年4月收治的51例过敏性紫癜患儿进行内镜检查,并分析其病变特征和临床的关系。结果51例患儿中,15例内镜下未见明显异常;36例有不同程度的胃、十二指肠和结肠的黏膜受损;其中,单纯胃镜下病变4例,单纯结肠镜下病变7例,胃、十二指肠和结肠同时出现病变25例。病变以黏膜渗出、糜烂、出血为主要特征。结论多数过敏性紫癜患儿存在胃肠道黏膜受累情况,有些病变早于皮肤紫癜出现之前,提示内镜检查对过敏性紫癜的早期诊断具有重要意义。
Objective To investigate the endoscopic lesion of children with Henoch-Schonlein purpura and its relationship with clinic and to provide basis for early diagnosis. Methods From January 2000 to April 2004, 51 children with Henoch-Schonlein purpura were examined by endoscopy. The relationship between the pathological features and clinical features was analyzed. Results Of the 51 children, no abnormality was seen in 15 cases under endoscopy. Thirty-six cases had mucosal lesions of stomach, duodenum and colon in varying degrees. Among them, 4 cases were under endoscopy alone and only under colonoscopy Seven cases, stomach, duodenum and colon lesions occurred simultaneously in 25 cases. Lesions mucosal exudation, erosion, bleeding as the main feature. Conclusion Most children with Henoch-Schonlein purpura have gastrointestinal mucosa involvement, and some lesions precede the appearance of purpura, suggesting that endoscopy is of great significance for the early diagnosis of Henoch-Schonlein purpura.