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目的 :通过实验观察胆克利脂胶囊增加胆汁分泌与平滑肌解痉的作用。方法 :采用大鼠胆汁引流和离体兔肠平滑肌运动等动物模型和实验方法。结果 :受试药物可显著增加大鼠胆汁分泌 ;抑制乙酰胆碱引起的家兔离体肠平滑肌痉挛。有关实验数据的统计分析显示 :受试药物组与生理盐水组比较或给药前后比较 ,差别有显著意义或非常显著意义 (P <0 .0 5或P<0 .0 1)。结论 :胆克利脂胶囊可明显增加胆汁分泌 ,解除平滑肌痉挛
Objective : To observe the effect of bile kelipid capsule on bile secretion and smooth muscle spasmolysis through experiments. Methods: Animal models and experimental methods such as bile drainage in rats and rabbit intestinal smooth muscle movement were used. RESULTS: The tested drugs significantly increased the secretion of bile in rats and inhibited the attenuated intestinal smooth muscle spasm induced by acetylcholine in isolated rabbits. Statistical analysis of the experimental data showed that there was a significant or very significant difference between the test drug group and the saline group (P<0.05 or P<0.01). Conclusion: Bilelipid capsules can significantly increase bile secretion and relieve smooth muscle spasm