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选取我院收治的肝硬化并上消化道出血患者112例,将其平均分为研究组和对照组56例。两组均采取补液、输血、奥美拉唑抑酸治疗,研究组在此基础上应用奥曲肽联合普萘洛尔治疗。结果研究组治疗的总有效率为96.43%,显著高于对照组80.36%(P<0.05);脾静脉血流量及门静脉血流量显著低于对照组及治疗前(P<0.05);两组不良反应发生率对比差异无统计学意义(P>0.05)。奥曲肽与普萘洛尔联合治疗肝硬化并上消化道出血疗效确切,可以有效且快速的止血,改善患者的血流动力学状态,安全性佳,适于临床应用。
A total of 112 patients with cirrhosis and upper gastrointestinal bleeding admitted to our hospital were selected and equally divided into study group (56 cases) and control group (56 cases). Two groups were taken rehydration, blood transfusion, acid treatment of omeprazole, the study group based on the application of octreotide combined with propranolol treatment. Results The total effective rate of the study group was 96.43%, significantly higher than that of the control group (80.36%, P <0.05). The splenic venous blood flow and portal vein blood flow were significantly lower than those of the control group and before treatment (P <0.05) There was no significant difference in the incidence of response (P> 0.05). Octreotide and propranolol combined treatment of cirrhosis and upper gastrointestinal bleeding is effective, can effectively and quickly stop bleeding, improve the patient’s hemodynamic status, good safety, suitable for clinical applications.