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关于纤维蛋白原基因型对血浆纤维蛋白原浓度的影响还有争议。基因型与动脉粥样硬化之间的关系尚无研究报告。本研究的目的是为了发现哪一种纤维蛋白原基因型与周围动脉粥样硬化有关。研究对象为两组55~74岁的人群,第一组为121例周围动脉疾病患者,第二组为年龄和性别与第一组匹配的126例健康对照
The impact of fibrinogen genotype on plasma fibrinogen concentration is still debatable. There is no research report on the relationship between genotypes and atherosclerosis. The purpose of this study was to find out which fibrinogen genotype is associated with peripheral atherosclerosis. The subjects were two groups of 55-74 years old, the first group of 121 patients with peripheral arterial disease, the second group of age and sex matched the first group of 126 healthy controls