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目的:探讨应用痔核注射术联合结扎痔上动脉的方式治疗孕妇痔疮出血的近远期疗效及安全性,为妊娠妇女痔疮治疗提供指导。方法:随机将76例妊娠痔出血妇女分成治疗组和对照组各38例,治疗组采用痔核注射术联合结扎痔上动脉的方式进行治疗,对照组采用地奥思明片(1.35 mg,2次/日)保守治疗。比较两组患者住院时间、VAS疼痛评分、不良反应、治愈率及复发情况。结果:治疗组的VAS评分1级为23例(50.53%),明显高于对照组的14例(36.84%),两组不良情况发生率比较无统计学差异(P=0.083)两组在VAS评分分布上治疗组明显优于对照组(Z=-2.06,P=0.038);治疗组不良情况发生率为2.63%,对照组为13.16%,两组不良情况发生率比较无统计学差异(P=0.083);平均住院时间治疗组(8.5±1.5)天,明显少于对照组的(13.5±5.5)天,两组差异具有统计学意义(t=5.407,P<0.05);治疗组的治愈有效率为100.00%,对照组为65.79%,治疗组明显优于对照组(P<0.05),治疗组无复发者,对照组有4例患者出现复发,对照组的复发率明显高于治疗组(P<0.05)。结论:对妊娠期痔出血采用痔核注射术联合结扎痔上动脉的方式能够有效提高治愈率及防止术后复发,并能够减轻患者的疼痛和减少住院时间。
Objective: To explore the short-term and long-term curative effect and safety of hemorrhoid injection combined with ligation of the hemorrhoid artery in the treatment of hemorrhoids hemorrhage in pregnant women and to provide guidance for the treatment of hemorrhoids in pregnant women. Methods: A total of 76 women with gestational hemorrhoids were randomly divided into treatment group (38 cases) and control group (38 cases). The treatment group was treated by hemorrhoids injection combined with ligation of the hemorrhoid artery. The control group was treated with gemcitabine (1.35 mg twice / Day) conservative treatment. The duration of hospital stay, VAS pain score, adverse reactions, cure rates and relapse were compared between the two groups. Results: There were 23 cases (50.53%) of VAS grade 1 in treatment group and 14 cases (36.84%) in control group. There was no significant difference in the incidence of adverse events between the two groups (P = 0.083) The score distribution of the treatment group was significantly better than that of the control group (Z = -2.06, P = 0.038). The incidence of adverse events was 2.63% in the treatment group and 13.16% in the control group. There was no significant difference in the incidence of adverse events between the two groups = 0.083). The average length of hospital stay was (8.5 ± 1.5) days, which was significantly lower than that of the control group (13.5 ± 5.5) days, the difference was statistically significant (t = 5.407, P <0.05) The effective rate was 100.00%, the control group was 65.79%, the treatment group was significantly better than the control group (P <0.05), the treatment group without recurrence, the control group, 4 patients relapsed, the control group, the recurrence rate was significantly higher than the treatment group (P <0.05). Conclusion: The hemorrhoids hemorrhage during pregnancy using hemorrhoids injection combined with ligation of the hemorrhoid artery can effectively improve the cure rate and prevent postoperative recurrence, and can reduce pain and reduce hospitalization time.