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目的:探讨肠内营养(EN)对慢阻肺急性加重期病人临床效果的影响。方法:选取2015年1月到2016年12月在我科治疗的慢阻肺急性加重期病人96例,随机分成观察组48例和对照组48例(常规饮食),二组病人均给予抗感染及相关对症治疗,观察组给予肠内营养支持治疗,2周后比较二组的血清蛋白和肺功能变化,观察两组病人抗菌药物使用天数、住院天数、3月内再入院率。结果:观察组在经治疗后血清白蛋白(ALB)、前白蛋白(PA)、FEV1、FEV1/FVC较对照组明显提高,抗菌药物使用天数、住院天数、3月内再住院率均明显降低,P<0.05,差异具有统计学意义。结论:肠内营养可以改善慢阻肺急性加重期病人的营养状况和肺功能,缩短住院时间及抗菌素使用天数,减少再住院率,促进病人康复,值得临床广泛使用。
Objective: To investigate the effect of enteral nutrition (EN) on the clinical effect of patients with COPD in acute exacerbation. Methods: A total of 96 acute exacerbation COPD patients treated in our department from January 2015 to December 2016 were selected and randomly divided into observation group (48 cases) and control group (48 cases) (conventional diet), and both groups were given anti-infection And the corresponding symptomatic treatment. The observation group was given enteral nutrition support. After two weeks, the serum protein and lung function of the two groups were compared. The days of antibacterial use, days of hospitalization, and readmission rates within 3 months were also observed. Results: Compared with the control group, the serum albumin (ALB), prealbumin (PA), FEV1 and FEV1 / FVC in the observation group were significantly increased after treatment, the number of days of antibiotic use, length of hospital stay, and readmission rate within 3 months were significantly lower , P <0.05, the difference was statistically significant. Conclusion: Enteral nutrition can improve the nutritional status and lung function, reduce the length of hospital stay and days of antibiotic use, reduce the rate of rehospitalization and promote the recovery of patients after acute exacerbation of chronic obstructive pulmonary disease. It is worth widely used in clinic.