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目的：明确食管及其下括约肌长度在胃食管反流疾病中的变化及临床意义。方法：用灌注式多导测压系统对正常组６３例受试者及胃食管反流组５３例病人进行食管压力测定。结果：正常人各年龄组食管下段括约肌长度差异无显著性；胃食管反流性疾病组食管下段括约肌长度及腹段下括约肌长度均显著下降；正常组与胃食管反流性疾病组身高与食管长度的相关系数分别为ｒ１＝０．７００，ｒ２＝０．７９８。结论：食管下括约肌长度在抗反流中起到重要作用，其在正常人群中不随年龄而变化；胃食管反流性疾病患者未伴食管长度缩短、上提
Objective: To clarify the changes of esophageal and lower sphincter length in gastroesophageal reflux disease and its clinical significance. Methods: Esophageal pressure was measured in 63 patients in the normal group and 53 patients in the gastroesophageal reflux group by perfusion multi-guided pressure measurement system. Results: There was no significant difference in the length of sphincter between lower esophagus and lower esophagus in all age groups. The length of esophageal sphincter and the length of lower sphincter of lower esophagus in gastroesophageal reflux disease group were significantly decreased. In normal group and gastroesophageal reflux disease group, The correlation coefficients of length are r1 = 0.700 and r2 = 0.798, respectively. CONCLUSIONS: The length of the lower esophageal sphincter plays an important role in anti-reflux, which does not change with age in normal subjects; patients with gastroesophageal reflux disease are not accompanied by esophageal length shortening,