单纯疱疹病毒(HSV)可引起生殖系统感染,妊娠期间感染能导致新生儿的HSV感染。本文对HSV发病机理、人体对HSV的免疫反应及流行病学、HSV类型的诊断、临床特征及抗病毒治疗进行综述。其目的在于对HSV及妊娠期感染进行全面的了解,对感染孕妇及胎儿有正确的认识,对感染后的治疗有所帮助。 Herpes simplex virus (HSV) can cause reproductive system infections, infection during pregnancy can lead to neonatal HSV infection. This article reviews the pathogenesis of HSV, human immune response to HSV and epidemiology, the diagnosis of HSV type, clinical features and antiviral therapy. Its purpose is to have a thorough understanding of HSV and gestational infection, to have a correct understanding of the infection of pregnant women and fetuses, and to be useful for post-infection treatment.