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目的探讨2型糖尿病与骨质疏松的关系和临床意义。方法对46例2型糖尿病患者进行骨密度测定及空腹血糖检查,并根据1年内数次血糖的平均值,分为控制较好组(血糖<7.8mmol/L)和控制差组(血糖≥7.8mmol/L),结合病程等相关因素进行研究分析。结果46例2型糖尿病患者中骨密度降低32例(69.6%),其中,女性患病率为83.3%。1年内血糖平均值两组均高于正常水平,骨密度降低者血糖水平相对更高,两组有显著差异(P<0.05)。结论2型糖尿病并发骨质疏松的患病率明显高于正常人群,女性偏高,病程在8年以上者明显;骨密度降低与长期空腹血糖水平过高密切相关。
Objective To investigate the relationship between type 2 diabetes and osteoporosis and its clinical significance. Methods The bone mineral density (BMD) and fasting plasma glucose (FBG) were measured in 46 patients with type 2 diabetes mellitus. According to the average number of blood glucose in one year, the patients were divided into control group (blood glucose <7.8 mmol / L) and control group mmol / L), combined with the course of disease and other related factors for research and analysis. Results The bone density in 46 patients with type 2 diabetes decreased by 32 (69.6%), of which the prevalence was 83.3% in women. The mean level of blood glucose in one year was higher than the normal level, while the level of blood glucose in the patients with decreased bone density was relatively higher. There was a significant difference between the two groups (P <0.05). Conclusions The prevalence of type 2 diabetes complicated with osteoporosis is significantly higher than that of normal people. The female is overweight and the course of disease is more than 8 years. The decrease of BMD is closely related to the long-term fasting blood glucose level.