目的:了解贵州省孕产妇中HIV、梅毒的感染现况。方法:2011年对贵州省88个县(市、区)的34万名孕产妇进行HIV、梅毒血清学检测,对检测结果进行分析。结果:全省孕产妇中HIV、梅毒检测阳性率分别为3.84/万、8.26/万,9个市(州)阳性率地区分布差异明显;HIV、梅毒阳性率呈正相关关系(Pearson相关系数R=0.876,P<0.01),提示艾滋病流行程度高的地区梅毒流行程度也高;134例HIV阳性孕产妇中以文化程度较低、农民/农民工为主。结论:摸清感染状况有助于政府部门制定艾滋病、梅毒防控策略和预防母婴传播策略,预防艾滋病、梅毒母婴传播应重点关注经济落后的农村、少数民族地区。 Objective: To understand the status of HIV and syphilis among pregnant women in Guizhou province. Methods: In 2011, 340,000 pregnant women in 88 counties (cities and districts) of Guizhou Province were tested for HIV and syphilis serology, and the results were analyzed. Results: The positive rates of HIV and syphilis in pregnant women in the province were 3.84 / million and 8.26 / million, respectively. There were significant differences in the distribution of positive rates among 9 cities (states); the positive rates of HIV and syphilis showed a positive correlation (Pearson correlation coefficient R = 0.876, P <0.01), suggesting that the prevalence of syphilis in HIV / AIDS-endemic areas is also high. Of the 134 HIV-positive pregnant women, those with low education and farmer / migrant workers were the most predominant. Conclusion: To find out the status of infection helps government departments to formulate AIDS prevention and control strategies and prevent mother-to-child transmission strategies and prevent AIDS. The mother-to-child transmission of syphilis should focus on economically backward rural areas and ethnic minority areas.