1971年Horan通过1184例尸检分析,发现有梗塞病灶的416例中,253例有异常Q波,敏感性为61%;无梗塞病灶的768例中,682例无异常Q波,特异性为89%,故异常Q波诊断心肌梗塞的平均可靠性为75%。过去认为,异常Q波是心肌穿壁性坏死产生的永久性损伤。但是动物实验和临床上均已观察到,异常Q波可以消失,并非一定见于穿壁性心肌梗塞。异常Q波消失的情况有两种:即短暂性Q波的消失;慢性Q波的消失。后者主要见于在某种情况下如冠状动脉搭桥术后,使心肌灌注重建。本文重点就短暂性异常Q波的常见病因,发病机制和临床意义等作一综述。常见病因 In 1971 Horan passed the autopsy analysis of 1184 cases and found that there were 253 cases of infarction lesions in 253 cases of abnormal Q wave, the sensitivity was 61%; 768 cases of non-infarction lesions, 682 cases without abnormal Q wave, specificity of 89 %, So the average reliability of abnormal Q wave diagnosis of myocardial infarction was 75%. In the past that the abnormal Q wave is a permanent myocardial damage caused by myocardial necrosis. However, it has been observed experimentally and clinically in animals that anomalous Q waves can disappear and may not necessarily be seen in those with transmyocardial infarction. Abnormal Q wave disappears in two situations: the disappearance of transient Q wave; disappearance of chronic Q wave. The latter is mainly seen in some cases, such as coronary artery bypass surgery, myocardial perfusion reconstruction. This article focuses on the common etiology, pathogenesis and clinical significance of transient abnormal Q waves. Common causes